Research

Publications

Ziegler C, Grundner-Culemann F, Schiele MA, Schlosser P, Kollert L, Mahr M, Gajewska A, Lesch K-P, Deckert J, Köttgen A & Domschke K: The DNA methylome in panic disorder: a casecontrol and longitudinal psychotherapy-epigenetic study. Translational Psychiatry 9:314; doi.org/10.1038/s41398-019-0648-6 (2019).

Sankowski R, Böttcher C, Masuda T, Geirsdottir L, Sagar, Sindram E, Seredenina T, Muhs A, Scheiwe C, Shah MJ, Heiland DH, Schnell O, Grün D, Priller J, Prinz M: Mapping microglia states in the human brain through the integration of high-dimensional techniques. Nat Neurosci 22(12):2098-2110; doi: 10.1038/s41593-019-0532-y (2019).

Dokalis N, Prinz M: Resolution of neuroinflammation: mechanisms and potential therapeutic option. Semin Immunopathol 41(6), 699-709;  doi: 10.1007/s00281-019-00764-1 (2019).

Lenz M, Ben Shimon M, Benninger F, Neufeld MY, Shavit-Stein E, Vlachos A, Maggio N: Systemic thrombin-inhibition ameliorates seizures in a mouse model of pilocarpine-induced status epilepticus. Journal of Molecular Medicine 97(3), 1-8; doi: 10.1007/s00109-019-01837-2 (2019).

Reinhardt A, Stichel D, Schrimpf D, Koelsche C, Wefers AK, Ebrahimi A, Sievers P, Huang K, Casalini MB, Fernández-Klett F, Suwala A, Weller M, Gramatzki D, Felsberg J, Reifenberger G, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Buslei R, Deckert M, Mawrin C, Hewer E, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Korshunov A, Reuss DE, Sahm F, Jones DTW, Capper D & von Deimling A: Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathol Commun 7(1), 163; doi: 10.1186/s40478-019-0801-8 (2019).

Nievergelt CM, Maihofer AX, Klengel T, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Dalvie S, Duncan LE, Gelernter J, Levey DF, Logue MW, Polimanti R, Provost AC, Ratanatharathorn A, Stein MB, Torres K, Aiello AE, Almli LM, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegovic E, Babić D, Bækvad-Hansen M, Baker DG, Beckham JC, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Børglum AD, Bradley B, Brashear M, Breen G, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Calabrese JR, Caldas-de-Almeida JM, Dale AM, Daly MJ, Daskalakis NP, Deckert J, Delahanty DL, Dennis MF, Disner SG, Domschke K, Dzubur-Kulenovic A, Erbes CR, Evans A, Farrer LA, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Geuze E, Gillespie C, Uka AG, Gordon SD, Guffanti G, Hammamieh R, Harnal S, Hauser MA, Heath AC, Hemmings SMJ, Hougaard DM, Jakovljevic M, Jett M, Johnson EO, Jones I, Jovanovic T, Qin XJ, Junglen AG, Karstoft KI, Kaufman ML, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kranzler HR, Kremen WS, Lawford BR, Lebois LAM, Lewis CE, Linnstaedt SD, Lori A, Lugonja B, Luykx JJ, Lyons MJ, Maples-Keller J, Marmar C, Martin AR, Martin NG, Maurer D, Mavissakalian MR, McFarlane A, McGlinchey RE, McLaughlin KA, McLean SA, McLeay S, Mehta D, Milberg WP, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Neale BM, Nelson EC, Nordentoft M, Norman SB, O’Donnell M, Orcutt HK, Panizzon MS, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Rice JP, Ripke S, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero K, Rung A, Rutten BPF, Saccone NL, Sanchez SE, Schijven D, Seedat S, Seligowski AV, Seng JS, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Trapido E, Uddin M, Ursano RJ, van den Heuvel LL, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Werge T, Williams MA, Williamson DE, Winternitz S, Wolf C, Wolf EJ, Wolff JD, Yehuda R, Young RM, Young KA, Zhao H, Zoellner LA, Liberzon I, Ressler KJ, Haas M, Koenen KC: International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun 10(1), 4558; doi: 10.1038/s41467-019-12576-w (2019).

Prinz M, Jung S, Priller J: Microglia Biology: One Century of Evolving Concepts. Cell 179(2), 292-311; doi: 10.1016/j.cell.2019.08.053 (2019).

Kierdorf K, Prinz M: Microglia: Same same, but different. J Exp Med 216(10), 2223-2225; doi: 10.1084/jem.20191535 (2019).

O’Connor T, Zhou X, Kosla J, Adili A, Garcia Beccaria M, Kotsiliti E, Pfister D, Johlke AL, Sinha A, Sankowski R, Schick M, Lewis R, Dokalis N, Seubert B, Höchst B, Inverso D, Heide D, Zhang W, Weihrich P, Manske K, Wohlleber D, Anton M, Hoellein A, Seleznik G, Bremer J, Bleul S, Augustin HG, Scherer F, Koedel U, Weber A, Protzer U, Förster R, Wirth T, Aguzzi A, Meissner F, Prinz M, Baumann B, Höpken UE, Knolle PA, von Baumgarten L, Keller U, Heikenwalder M: Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell 36(3), 250-267.e9; doi: 10.1016/j.ccell.2019.08.001 (2019).

Büttner C, Heer M, Traichel J, Schwemmle M & Heimrich B: Zika Virus-Mediated Death of Hippocampal Neurons Is Independent From Maturation State. Front Cell Neurosci 13, 389; doi: 10.3389/fncel.2019.00389 (2019).

Kneer K, Reinhard J, Ziegler C, Slyschak A, Schiele M, Vietz M, Peters K, Meisenzahl EM, Pauli P, Reif A, Deckert J, Romanos M, Domschke K, Neufang S: Serotonergic influence on depressive symptoms and trait anxiety is mediated by negative life events and frontal activation in children and adolescents. Eur Child Adolesc Psychiatry; doi: 10.1007/s00787-019-01389-3 (2019).

Lenz M & Vlachos A: The neuroimmunological synapse: from synaptic homeostasis to brain disease. Neuroforum 25(3); doi:10.1515/nf-2019-0 (2019).

Böttcher C, Sankowski R, Priller J, Prinz M: CNS myeloid cell heterogeneity at the single-cell level. Neuroforum 25(3); doi:10.1515/nf-2018-0034 (2019).

Kierdorf K, Masuda T, Jordão MJC, Prinz M: Macrophages at CNS interfaces: ontogeny and function in health and disease. Nat Rev Neurosci 20(9), 547-562; doi: 10.1038/s41583-019-0201-x (2019).

Schiele MA, Kollert L, Lesch K-P, Arolt V, Zwanzger P, Deckert J, Ziegler C, Domschke K: Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression? Eur Neuropsychopharmacol 29(10), 1161-1167; doi: 10.1016/j.euroneuro.2019.07.131 (2019).

Priller J, Prinz M: Targeting microglia in brain disorders. Science 365(6448), 32-33; doi: 10.1126/science.aau9100 (2019).